Endocrine Abstracts

A provisional diagnosis of paroxysmal atrial fibrillation with normal blood pressure and echocardiogram was made in a 58 years old man. He described ‘funny turns’ on standing during which he would become sweaty, tremulous with palpitations and headache and facial flushing preceded by pallor. The patient was otherwise fit and healthy with a BMI of 27.3 kg/m2; he used to drink about 15 pints of beer per week and smoke 11 cigarettes daily for the last 40 year...

Polychlorinated biphenyls (PCBs) are persistent environmental pollutants. Two industrial PCB mixtures, Aroclors 1221 and 1254 have been suggested to have estrogenic and anti-estrogenic properties, respectively. We have examined whether these PCB mixtures modulated bone formation and resorption in intact and ovariectomized (ovx) rat models. Twentyfour adult female rats were divided into three groups subcutaneously receiving 4% DMSO (Control), Aroclor 1221 (10 mg/kg) and Aroclor...

Differentiating aldosterone-producing adenomas (APA) from bilateral adrenal hyperplasia (BAH) as a cause of Conn’s syndrome (CS) is crucial for appropriate management. We have prospectively evaluated the relative contributions of PST, adrenal imaging by Computed Tomography (CT) and AVS in the differential diagnosis of CS.We investigated 25 consecutive patients with CS referred to our unit with an identical protocol. Every patient underwent PST, CT a...